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Updated: Jan 12, 2026

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骨肉瘤的小鼠模型:揭开疾病机制,加速药物发现和开发

Staci L Haney1, Sarah A Holstein1

  • 1Department of Internal Medicine, University of Nebraska Medical Center, Omaha, Nebraska, USA.

Cancer reports (Hoboken, N.J.)
|October 31, 2025
PubMed
概括

骨髓瘤小鼠模型对于开发新疗法至关重要. 这些模型有助于评估向疗法和免疫疗法,推进对抗这一具有挑战性的骨癌的斗争.

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相关概念视频

Mouse Models of Cancer Study02:43

Mouse Models of Cancer Study

Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...
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