相关实验视频

Updated: Jul 17, 2026

Application of CRISPR Interference (CRISPRi) for Gene Silencing in Pathogenic Species of Leptospira
14:49

Application of CRISPR Interference (CRISPRi) for Gene Silencing in Pathogenic Species of Leptospira

Published on: August 14, 2021

在Acinetobacter baumannii中,BaeR和H-NS控制了CRISPR-Cas介导的免疫力和毒性

Ting Yu1, Jun Xie2, Xinyue Huang3

  • 1The First School of Clinical Medicine, Faculty of Medicine, Yangzhou University, Yangzhou, China.

mSystems
|October 31, 2025
PubMed
概括

由 BaeR 和 H-NS 调节的 Acinetobacter baumannii 的 CRISPR-Cas 系统通常会抑制毒性. 删除Cas3释放了这种控制,增强了生物膜的形成和致病性,揭示了新的药物标.

关键词:
这种细菌是Acinetobacter baumannii.这是 BaeRR.这就是CRISPR-Cas.在H-NS中,我们可以使用H-NS.生物膜是一种生物膜.免疫力是一种免疫力.毒性 毒性是一种毒性.

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