相关实验视频

Updated: Jan 12, 2026

Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery

Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery

Published on: September 27, 2024

与TyG相关的指数与结直肠癌风险之间的关联:一个前性队列研究

Runxue Jiang¹, Shushan Xing², Xia Wang³

¹Department of Oncology Surgery, North China University of Science and Technology Affiliated Tangshan People's Hospital, Tangshan, China.

International journal of cancer

|October 31, 2025

概括

与甘油三糖 (TyG) 相关的指数升高与结直肠癌 (CRC) 风险增加有关. 这些标记物,包括TyG-BMI,TyG-WC和TyG-WHtR,可以帮助评估CRC风险.

科学领域:

代谢综合征和癌症流行病学
在瘤学中发现生物标志物

背景情况:

胰岛素抵抗是结直肠癌 (CRC) 的已知危险因素.
三甘油-葡萄糖 (TyG) 相关指数是胰岛素耐药性的新兴生物标志物.
TyG指数与CRC风险之间的关联需要进一步调查.

研究的目的:

评估三种与TyG相关的指数与CRC风险之间的关系.
评估TyG-BMI,TyG-WC和TyG-WHtR作为CRC风险分层的生物标志物的潜力.

主要方法:

一项大型前性队列研究 (Kailuan研究,2006-2019) 涉及173,342名没有癌症的参与者.
随访时间中位数为14.23年,发现977例CRC病例.
使用多变量Cox比例危险模型和剂量反应分析.

主要成果:

在高的TyG-BMI,TyG-WC和TyG-WHtR和增加的CRC风险之间发现了显著的积极关联.
风险比率随着TyG指数的四分位数较高而增加,这表明了剂量-反应关系.
对于所有测试的TyG指数,观察到线性关系.

结论:

与TyG相关的指数升高与患结直肠癌的风险更高有显著关联.
这些TyG指数表明,通过CRC风险对个人进行分层的潜在实用性.
进一步的研究可以探索TyG指数在CRC预防策略中的临床应用.

关键词:

与 TyG 相关的指数队列研究是一项队列研究.结肠直肠癌是什么意思

更多相关视频

Author Spotlight: Unveiling Transmembrane Protein Family-Related Markers in Gastric Cancer and Implications for Targeted Therapies

Author Spotlight: Unveiling Transmembrane Protein Family-Related Markers in Gastric Cancer and Implications for Targeted Therapies

Published on: September 15, 2023

Evaluation of Colorectal Cancer Risk and Prevalence by Stool DNA Integrity Detection

Evaluation of Colorectal Cancer Risk and Prevalence by Stool DNA Integrity Detection

Published on: June 8, 2020

相关概念视频

Cancer Prevention

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...