探索儿童心脏手术后的结果中的种族和种族差异:一个NEPHRON研究分析分析
Jiaxin Huang1, Huaiyu Zang2, Garrett Reichle3
1Division of Pediatric Critical Care, Department of Pediatrics, University of California, San Francisco, San Francisco, USA.
Pediatric cardiology
|October 31, 2025
概括
与心脏手术相关的急性损伤 (CS-AKI) 率在新生儿中没有因种族/种族而异. 虽然液体平衡的实现有所不同,但在死亡率或停留时间方面没有发现显著差异.
科学领域:
- 新生儿重症监护的新生儿重症监护
- 儿科病学 儿科病学
- 心血管外科手术的结果
背景情况:
- 新生儿术后结果的种族和种族差异已被记录.
- 新生儿中与心脏手术相关的急性损伤 (CS-AKI) 的差异仍未得到研究.
- 新生儿的先天性心脏手术对功能提出了独特的挑战.
研究的目的:
- 评估CS-AKI患病率和结果中的种族和民族差异.
- 在接受先天性心脏手术的新生儿中调查CS-AKI的差异.
- 根据种族/种族来确定术后结果的潜在变化.
主要方法:
- 对22个中心的2,165名新生儿进行了回顾性队列研究 (2015-2018).
- 种族/种族分为八个组;CS-AKI根据新生儿修改的KDIGO标准定义.
- 结果包括液体平衡,呼吸支,停留时间和死亡率;使用多变量回归分析.
主要成果:
- CS-AKI的患病率 (轻度31%,重度23%) 在种族/族群之间没有差异.
- 非西班牙裔黑人 (NHB) 新生儿出生时体重较低,手术复杂性更高;非西班牙裔白人 (NHW) 新生儿的私人保险更高.
- 与NHW新生儿相比,NHB新生儿在POD 3时实现净负流体平衡的可能性较低;在调整后,其他结果没有差异.
结论:
- 在接受先天性心脏手术的新生儿中,CS-AKI的发病率在不同种族和族群中是一致的.
- 观察到流体平衡成就差异,但与死亡率或通风持续时间的显著差异无关.
- 这项研究强调了新生儿心脏手术后监测功能的重要性,没有显著的种族/民族结果差异.
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