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提高MR细胞计在前列腺癌成像中的诊断效果

Jiahui Zhang¹, Fan Liu², Qianyu Peng^1,3

¹Department of Radiology, State Key Laboratory of Complex Severe and Rare Disease, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.

Abdominal radiology (New York)

|October 31, 2025

概括

消除输液效应和在MR细胞计中使用组图特征显著提高了区分良性和恶性前列腺病变的准确性. 这种非侵入性技术提高了前列腺癌检测的诊断效果.

科学领域:

医疗成像医学成像
在瘤学瘤学.
生物物理学的生物物理.

背景情况:

前列腺癌的诊断依赖于良性和恶性病变的准确区分.
非侵入性成像技术对于提高诊断效率至关重要.
核磁共振细胞计为微观结构成像提供了潜在的可能性,但需要改进.

研究的目的:

为了评估MR细胞计的增强诊断性能.
评估消除输液效应对诊断准确性的影响.
为了研究组图特征在区分前列腺病变中的实用性.

主要方法:

在72名患者中使用了依赖时间的扩散MRI (PGSE和OGSE DWI).
应用单指数合以消除 perfusion 效应.使用单指数合以消除 perfusion 效应.
计算的明显扩散系数 (ADC),MR细胞计参数和分析的组图特征.

主要成果:

消除输液效应增加了病变类型之间的细胞直径差异的意义.
组图特征显示诊断效果与平均ADC或微观结构参数相当.
输液去除和组织谱结合的联合策略将AUC提高到0.934.

结论:

消除输液效应和组图特征的整合提高了MR细胞计的诊断效率.
这些联合策略改善了良性和恶性前列腺病变的分化.
核磁共振细胞测量显示为前列腺癌评估的非侵入性工具具有前景.

关键词:

扩散式核磁共振成像 (MRI)历史图的特征是历史图的特征.冲动的冲动是一种冲动.perfusion 输液是一种输液.前列腺病变的病变前列腺病变

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