第二代失焦结合多段眼镜镜片对快速进展的近视的近视控制有效性:随机对照试验的研究协议
Ying Hon1, Rachel Ka Man Chun1,2,3, Tsz Wing Leung1,2,3
1Centre for Myopia Research, School of Optometry, The Hong Kong Polytechnic University, Kowloon, Hong Kong, China.
PloS one
|October 31, 2025
概括
新的失焦纳入多段 (DIMS) 眼镜镜片显示出控制儿童近视进展的前景. 这项试验评估了它们在高风险儿科近视病例中的有效性.
科学领域:
- 眼科医生 眼科 眼科
- 儿科光学测量 儿科光学测量
- 近视控制研究近视研究
背景情况:
- 对近视控制的眼镜干预措施是非侵入性的,但已显示出适度的长期疗效.
- 现有的方法对于患有早期发作和快速进展的近视的高风险儿童是不够的.
研究的目的:
- 评估新一代脱焦内置多段 (DIMS) 眼镜镜片在减缓近视进展方面的有效性.
- 评估DIMS透镜在患有早期近视和快速进展的儿童中的有效性.
主要方法:
- 与中国学龄儿童 (4-12岁) 进行前性,双面罩,主动控制,随机化试验.
- 参与者近视度至少为-0.75 D,并且进展快 (≥0.50 D/年) 或轴向增长 (≥0.27 mm/年).
- 随机分配到新一代DIMS镜头,单视镜头 (控制) 或销售的DIMS镜头 (辅助),以1:1:1的比例.
主要成果:
- 主要结局:12个月后循环客观折射的变化.
- 二次结果:12个月后轴长度的变化.
- 探索与近视控制有效性相关的外周折射和胸腔厚度.
结论:
- 这项研究将提供有关先进的DIMS技术在治疗儿科近视的有效性的见解.
- 结果旨在支持基于证据的实践,用于高风险进展的儿童的近视管理.
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