牙周内科临床和翻译研究的进展:全面的概述
Renato Menezes Silva1, Gor Bassi Ferreira Petean2, Claudio Mendes Pannuti3
1Department of Endodontics, University of Pittsburgh School of Dental Medicine, Pittsburgh, PennsylvaniaUSA.
Brazilian dental journal
|October 31, 2025
概括
临床和转化研究对于以证据为基础的内科医生至关重要. 影像学和分子生物学方面的进步改善了诊断和理解,为精密牙科铺平了道路.
科学领域:
- 牙周内科医院 牙周内科医院 牙周内科医院
- 翻译科学 翻译科学
- 基于证据的牙科.
背景情况:
- 临床和翻译研究对于推动内牙科的发展至关重要.
- 本综述综合了目前内牙科研究的进展,涵盖了方法,诊断和技术.
研究的目的:
- 提供关于牙周内科医学的临床和翻译研究的全面概述.
- 识别挑战并突出新兴技术和未来方向.
主要方法:
- 关于牙周内科临床和翻译研究的当前文献的叙述性综述.
- 专注于随机对照试验,结果定义,患者报告的结果,高级成像 (CBCT) 和分子生物学技术 (PCR).
主要成果:
- 圆束计算断层扫描 (CBCT) 提高了诊断准确性和治疗监测.
- 分子技术加深对内牙微生物群,免疫反应和宿主因素的理解.
- 局限性包括诊断不准确性,缺乏标准化的标准,以及生物标志物和omics数据的不足利用.
结论:
- 精密牙科,整合基因组学,生物信息学和人工智能,承诺个性化的内牙护理.
- 严格的研究设计,多中心合作和分子诊断对于未来的进展至关重要.
- 翻译科学是重塑牙周内科医学的未来和优化患者治疗结果的关键.
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