在美洲,第一次从人类中分离出Mycobacterium brisbanense
Carlos Eduardo Dias Campos1, Rachel Dos Santos de Sena Vasconcelos1, William Marco Vicente da Silva1
1Fundação Oswaldo Cruz-Fiocruz, Escola Nacional de Saúde Pública, Centro de Referência Professor Hélio Fraga, Laboratório de Referência Nacional de Tuberculose e Micobacterioses, Rio de Janeiro, RJ, Brasil.
布里斯班尼菌 (Mycobacterium brisbanense) 是一种罕见的非结核菌,在美洲的人类分离物中被发现. 基因分析证实这些菌株是M. brisbanense,具有与类型菌株相似的药物敏感性概况.
科学领域:
- 微生物学 微生物学
- 遗传学 是一个遗传学.
- 传染性疾病 传染性疾病
背景情况:
- 布里斯班尼菌 (Mycobacterium brisbanense) 是一种罕见的非结核菌.
- 在美洲首次检测到人类突出显示了全球潜在的报告不足.
- 对此类物种的研究对于公共卫生来说越来越重要.
研究的目的:
- 报告和分析美洲第一批7个人类M. brisbanense分离物.
- 为了描述来自六名巴西患者的这些隔离物.
- 为了有助于对这种罕见的真菌菌菌的理解.
主要方法:
- 对hsp65,rpoB和16srRNA基因进行测序.
- 用于物种识别的遗传树的构建.
- 药物敏感性概况的确定.
主要成果:
- 测序的基因与M. brisbanense类型菌株具有很高的相似性.
- 通过遗传学分析,巴西的分离物被证实是M. brisbanense.
- 药物敏感性概况与类型菌株基本相似,除了塞福西丁和多西环素.
结论:
- 所有七种研究的菌株都被确定为Mycobacterium brisbanense.
- 这些发现证实了M. brisbanense在美洲的存在.
- 这项研究提供了有关M. brisbanense的遗传和易感性特征的宝贵数据.
更多相关视频
10:04Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
Published on: September 5, 2017
09:02An Experimental Model to Study Tuberculosis-Malaria Coinfection upon Natural Transmission of Mycobacterium tuberculosis and Plasmodium berghei
Published on: February 17, 2014
相关概念视频
Pulmonary Tuberculosis I
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Pulmonary Tuberculosis IV
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Pulmonary Tuberculosis II
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Pulmonary Tuberculosis III
The first classification is based on the development of the disease, and it includes the following categories:
Pulmonary Tuberculosis V
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
