人工甜味剂的潜在健康风险 人工甜味剂的潜在健康风险
Maria Effenberger1, Herbert Tilg1
1Department of Internal Medicine I: Gastroenterology, Hepatology, Endocrinology & Metabolism, Medical University of Innsbruck, Innsbruck, Austria;
Annual review of medicine
|October 31, 2025
概括
人工甜味剂可能会增加食欲,导致肥胖和2型糖尿病和心血管疾病的风险更高. 需要进一步的研究来确认它们的长期安全性和对癌症生物学的影响.
科学领域:
- 营养科学 营养科学
- 代谢健康 代谢健康
- 致癌研究 致癌研究
背景情况:
- 人工甜味剂是全球普遍存在的食品添加剂.
- 人们对它们对人类健康和新陈代谢的影响存在担忧.
- 现有的研究对其安全性提出了相互矛盾的证据.
研究的目的:
- 审查人工甜味剂对代谢健康的影响.
- 评估人工甜味剂消费与心血管疾病风险之间的关联.
- 为了检查人工甜味剂对癌症发展的潜在影响.
主要方法:
- 关于人工甜味剂的最新研究的文献综述.
- 分析临床前和流行病学数据.
- 关于代谢,心血管和致癌作用的证据综合.
主要成果:
- 人工甜味剂可能会刺激食欲,导致卡路里摄入量增加和肥胖.
- 与甜味剂相关的代谢变化与2型糖尿病和心血管疾病的风险增加有关.
- 临床前数据表明,它可能在影响癌症生物学和瘤进展方面发挥作用.
结论:
- 人工甜味剂可能对代谢健康构成风险,并增加肥胖的可能性.
- 人工甜味剂的消费与2型糖尿病和心血管疾病的风险增加有关.
- 进一步的研究至关重要,以确定人工甜味剂在癌症和整体健康方面的长期安全性.
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