系统性免疫炎症指数对深静脉血栓症的预测值:一个元分析
Xiaoxiao Chen1, Yuntao Mao1, Yuxin Ge1
1Department of Nursing, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310003, China.
Thrombosis research
|October 31, 2025
概括
系统性免疫炎症指数 (SII) 的升高与深静脉血栓症 (DVT) 的更高风险有关. 这种炎症标志物显示出潜在的潜力,作为对DVT风险评估的有价值预测因素.
科学领域:
- 医学研究 医学研究
- 炎症标志物的炎症标志物
- 血栓形成的研究.
背景情况:
- 系统性免疫炎症指数 (SII) 是一个新兴的炎症标志物.
- SII被认为是各种恶性瘤和炎症状况的预测指标.
- 越来越多的注意力集中在SII和深静脉血栓症 (DVT) 之间的关联上.
研究的目的:
- 系统地评估SII和DVT之间的关系.
- 为了确定SII是否可以作为DVT风险的预测标记.
主要方法:
- 在2025年1月6日之前,在Embase,Web of Science,Cochrane图书馆和PubMed进行了全面的文献搜索.
- 包括观察性研究,调查SII和DVT之间的联系.
- 使用MetaDisc和StataMP进行了元分析和诊断性能评估.
主要成果:
- 分析了14项涉及13,655名参与者的研究.
- 与对照组相比,患有DVT的个体的SII水平显著更高 (WMD = 938.60,p < 0.001).
- 升高的SII与4.73倍的DVT风险增加有关 (p < 0.001),具有良好的诊断性能 (AUC = 0.81).
结论:
- 较高的SII水平与发展DVT的可能性增加相关.
- SII显示出作为预测DVT风险的有价值生物标志物的潜力.
- 这些发现支持SII在对DVT的临床风险评估中的有用性.
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