无生物应激诱导的循环RNA:对植物应激耐受性的影响
Érika Frydrych Capelari1, Thomaz Stumpf Trenz1, Márcia Margis-Pinheiro1
1Department of Genetics, Federal University of Rio Grande do Sul, Brazil, Bento Gonçalves Avenue, 9500, Sector 4, Building 43333, Agronomia District, Porto Alegre, Rio Grande do Sul, 91540-000, Brazil.
Plant physiology and biochemistry : PPB
|October 31, 2025
概括
循环RNAs (circRNAs) 是植物适应干旱和度等非生物压力的关键调节者. 了解circRNA功能为开发适应环境挑战的作物提供了潜力.
科学领域:
- 植物生物学 植物生物学
- 分子生物学分子生物学
- 遗传学 是一个遗传学.
背景情况:
- 生物压力 (干旱,盐度,极端温度,营养不平衡) 显著降低了全球作物产量.
- 非编码RNAs,特别是循环RNAs (circRNAs),正在成为植物应激适应的关键调节者.
- 循环RNAs是稳定的,由组织特异性表达的回合拼接形成的共价闭环转录.
研究的目的:
- 审查关于在非生物压力下植物中circRNA生物发生,检测和功能的当前见解.
- 突出circRNAs在植物耐压力机制中的作用.
- 探索工程性circRNAs在作物改善方面的潜力.
主要方法:
- 关于植物circRNAs和非生物压力的实验研究的文献综述.
- 分析测序数据,识别跨植物物种的circRNAs.
- 检查功能机制,包括circRNA-miRNA-mRNA相互作用.
主要成果:
- 在许多植物物种中已经确定了circRNAs,并参与了发育和非生物应激反应.
- 循环RNAs通过菌微RNAs (miRNAs) 作为竞争的内源RNAs (ceRNAs) 起作用,调节基因表达.
- 证据将circRNA-miRNA-mRNA网络与植物对干旱,盐度,极端温度,金属毒性和营养压力的耐受性机制联系起来.
结论:
- 循环RNAs通过复杂的调节网络在植物非生物应激适应中发挥重要作用.
- 对circRNA功能的进一步研究可以推进基于RNA的策略,用于开发抗压作物.
- 工程化circRNAs代表了一个有希望的,尽管是投机的,增强作物特征的未来方向.
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