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Updated: Apr 30, 2026

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在一种新的iPSC衍生的肝细胞瘤模型中,PAGE4的上调调节促进了肝细胞瘤的进展

Issei Kawakita1, Shohei Honda2, Yuta Yamada3

  • 1Department of Pathology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Hokkaido, Japan; Department of Gastroenterological Surgery Ⅰ, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Hokkaido, Japan.

Biochemical and biophysical research communications
|October 31, 2025
PubMed
概括

研究人员使用人类干细胞开发了一种新的肝细胞母细胞瘤模型. 这种模型将前列腺相关基因4 (PAGE4) 确定为瘤生长的关键驱动因素,表明它是儿科肝癌的有希望的治疗标.

关键词:
肝炎母细胞瘤是什么?第4页 4页 4页 4页 4页 4页哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈这就是 iPSC 的意义.这是一种β-catenin.

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