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Updated: Jan 12, 2026

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解读上腺素类似放射性药物的对有机阴离子转运器亲和力的结构影响

Saskia Mühlig1, Xinyu Chen2, Anna Tutov3

  • 1Department of Nuclear Medicine and Comprehensive Heart Failure Center, University Hospital Würzburg, Würzburg, Germany.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
|October 31, 2025
PubMed
概括

针对北上腺素转运体 (NET) 的放射性追踪剂的结构性修改可以减少有机阴离子转运体 (OCT) 的吸收. 这项研究确定了设计更有选择性的NET配体的关键因素,这些配体具有更好的异位潜力.

关键词:
竞争性的细胞吸收.神经内分泌瘤是一个神经内分泌瘤.上腺素运输体 - - 上腺素运输体有机电离子载体运输器聚乙烯 (PET) 辐射追踪器

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