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Updated: Jan 12, 2026

Generation of Human Primordial Germ Cell-like Cells at the Surface of Embryoid Bodies from Primed-pluripotency Induced Pluripotent Stem Cells
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Published on: January 11, 2019

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在小鼠和人类多能细胞中抑制原始内皮命运的EZH2-PRC2的保存功能

Junyu Chen1, Boyan Huang2, Xuzhao Zhai3

  • 1GMU-GIBH Joint School of Life Sciences, The Fifth Affiliated Hospital of Guangzhou Medical University, Guangzhou National Laboratory, Guangzhou Medical University, Guangzhou 510005, China; Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou 510080, China; School of Life Science, South China Normal University, Guangzhou 510005, China.

Stem cell reports
|October 31, 2025
PubMed
概括

增强质同源2 (EZH2) 抑制促进了原始内皮细胞命运,通过减少H3K27me3标记,保护多能性. 这种表观遗传机制在整个物种中得到保护,影响了早期的胚胎发育.

关键词:
在EZH2-PRC2复合体中.这就是为什么PrESCs.低血清细胞的低血清细胞.多能干细胞是一种多能干细胞.原始的内皮原始的内皮.原始的内皮干细胞原始的内皮干细胞通过转差异化转化.

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