青少年功能连接体由一个稀疏的认知和拓枢纽核心动态控制
Jethro Lim1, Ilias Mitrai2, Prodromos Daoutidis3
1Department of Pediatrics, Division of Adolescence and Young Adult Medicine, Boston Children's Hospital, Boston, MA 02115, USA.
NeuroImage
|October 31, 2025
概括
关键的大脑区域在发育过程中保持对青少年连接体的控制. 这表明基本的大脑控制机制是稳定的,尽管正在进行成熟,但有助于认知功能.
科学领域:
- 神经科学是一个神经科学.
- 认知科学 认知科学
- 系统生物学 系统生物学
背景情况:
- 了解青少年大脑发育对于认知功能至关重要.
- 大脑在青春期适应认知需求的能力尚不清楚.
- 青少年大脑认知发展 (ABCD) 研究提供了关于这个发育时期的纵向数据.
研究的目的:
- 通过反控制框架调查青少年功能连接体的可控性.
- 为了确定在青春期保持对大脑网络控制的关键大脑区域.
- 检查这些控制机制的发展稳定性.
主要方法:
- 使用了一种促进度的反控制框架.
- 分析了ABCD研究中的静止状态功能磁共振成像 (fMRI) 数据 (n=1394).
- 估计的关键反成本,以评估区域控制行动在connectome.
主要成果:
- 一组核心高度连接的区域始终保持对连接组的控制,即使在高反成本下.
- 这些关键区域包括视觉,头部,部和前额头部区域.
- 这些地区的控制行动在整个青春期都在发育上保持稳定,反成本没有显著变化.
结论:
- 大脑网络可控性的基本机制在青春期似乎已发展得很好.
- 这些稳定的控制机制可能有助于信息处理和对认知需求的响应.
- 尽管正在进行的成熟和网络变化,核心大脑控制系统仍然很强大.
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