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患有自发冠状动脉剖析的患者上升性大动脉扩张的患病率
Luke Dreher1, Hussein Abdul Nabi1, George Bcharah1
1Department of Cardiovascular Medicine, Mayo Clinic Arizona, USA.
概括
上升性大动脉扩张影响约20%的自发冠状动脉解剖 (SCAD) 患者,表明SCAD是一种全身血管问题. 建议SCAD患者进行基线大动脉评估.
科学领域:
- 心脏病学 心脏病学
- 血管医学 血管医学
- 放射学 放射学是指放射学
背景情况:
- 自发冠状动脉解剖 (SCAD) 是一种已知的急性冠状动脉综合征的原因,特别是在年轻女性中.
- SCAD通常与全身血管异常有关,但这些患者的上升性大动脉扩张尚不清楚.
研究的目的:
- 确定SCAD患者上升大动脉扩张的患病率和临床意义.
- 调查SCAD中上升大动脉扩张与患者人口统计学和其他血管异常的关联.
主要方法:
- 一项回顾性多中心队列研究包括937名血管学确认的SCAD患者.
- 跨胸腔心声扫描用于测量大动脉尺寸,扩张以年龄,性别和身体表面积调整的参考值来定义.
主要成果:
- 在SCAD患者中有20.2%发现了上升性大动脉扩张,最常见的是上升性大动脉中部.
- 扩张的患病率随着年龄的增长而增加,并与高血压和冠外动脉瘤有关.
- 胸前大动脉切割很少发生 (0.4%).
结论:
- 上升性大动脉扩张在SCAD患者中明显比一般人群更常见,支持SCAD作为系统性血管疾病.
- 基线大动脉评估可能对SCAD患者有价值.
- 未来的研究应该集中在SCAD中大动脉扩张的进展,后果和监测策略上.
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