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预流结构,HSV-1糖蛋白B的逃避和中和

Ryan S Roark1,2,3, Andrew J Schaub4, Wei Shi4

  • 1Aaron Diamond AIDS Research Center, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA.

Nature microbiology
|November 1, 2025
PubMed
概括

研究人员稳定了简单疹病毒1糖蛋白B (HSV-1 gB) 在其预注射形式. 一种新型抗体通过准重新折叠的区域来中和HSV-1,揭示了病毒逃避的机制.

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