绿色暴露和空气污染对不同时间尺度上的缺血性中风死亡率的双向效应修改
Bingyin Zhang1, Qiyong Cao2, Qiongqi Zhang2
1Shandong Center for Disease Control and Prevention, Jinan, China.
BMC public health
|November 1, 2025
概括
绿色暴露显著降低缺血性中风 (IS) 患者的死亡风险,特别是在空气污染较高的地区. 这凸显了城市绿化对公共卫生和中风恢复的重要性.
科学领域:
- 环境健康 环境健康
- 流行病学 流行病学
- 心血管研究研究心血管研究
背景情况:
- 缺血性中风 (IS) 是全球死亡和残疾的主要原因.
- 暴露于绿色的健康益处是众所周知的,但它对IS患者死亡率和与空气污染相互作用的影响需要进一步调查.
研究的目的:
- 为了研究绿色暴露 (NDVI/EVI) 与大量IS患者队列中的死亡风险之间的关联.
- 检查空气污染对暴露于绿色和IS死亡率之间的关系的影响.
主要方法:
- 来自中国的249537名IS患者 (2013-2019) 的队列使用多级Cox比例危险模型进行了分析.
- 评估了累积和同时发生的NDVI/EVI与死亡率之间的关联,考虑了高分辨率的空气污染物数据.
- 限制性立方线模型和子组分析被用于探索暴露-反应关系并确定脆弱人群.
主要成果:
- 增加绿色暴露 (NDVI) 与减少全因,心血管和中风死亡率有关.
- 累积的NDVI显示出比同期的NDVI更强的保护作用,分别具有线性反向和U形关联.
- 保护作用在老年人,城市居民和男性中得到放大,特别是在高空气污染的情况下;绿色减轻了空气污染的死亡风险.
结论:
- 绿色的暴露显著降低了在不同时间尺度的IS患者的死亡风险.
- 绿色的保护作用在空气污染较高的地区得到增强,NO2被确定为一个重要的修饰因素.
- 研究结果支持在高空气污染地区进行绿化干预,以改善IS幸存者的结果.
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