在使用修改后的Delphi技术治疗骨质疏松症的抗吸收药物之前,重新评估牙清除方案
Sarah Kho Xian Chua1, Ruth Wei Choe1, Catherine Hsu Ling Hong2
1National University Centre for Oral Health Singapore, Singapore, Singapore.
BMC oral health
|November 1, 2025
概括
在抗吸收剂 (ARA) 治疗前的牙清洁应该与风险相适应. 共识陈述指导临床医生为接受ARA治疗的患者量身定制牙清除方案,以预防与药物相关的骨缩 (MRONJ).
科学领域:
- 口腔和牙面部外科手术
- 牙科瘤学 牙科瘤学
- 药理学 药理学是指药理学的学科.
背景情况:
- 接受抗吸收剂 (ARA) 治疗的患者面临与药物相关的下巴骨硬化 (MRONJ) 的风险.
- 目前的指导方针缺乏具体的细节,用于在ARA治疗开始前进行风险适当的牙科清除计划.
研究的目的:
- 在开始ARA治疗之前,为风险适当的牙清除协议制定共识陈述.
- 为在患有MRONJ风险的患者中管理牙健康提供指导.
主要方法:
- 一个由13人组成的多学科专家小组使用了修改后的Delphi过程.
- 文献审查和专家意见确定了7个领域和29个声明.
- 在29份声明中,有23份在两轮投票后达成共识.
主要成果:
- 在根据患者病史和紧急情况量身定制治疗计划方面达成了共识.
- 为管理有症状的牙,,牙周病和牙科植入物提出了建议.
- 在ARA治疗之前制定了专门的指导方针来管理牙科问题,但由于证据不足而排除了儿科患者.
结论:
- 临床医生应根据个体患者的风险因素定制牙清除协议.
- 达成共识的声明旨在优化患者护理,并最大限度地降低MRONJ风险.
- 在ARA治疗之前,需要进一步研究儿科患者的治疗方法.
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