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Isolation of Cortical Microglia with Preserved Immunophenotype and Functionality From Murine Neonates
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微质NLRC5驱动 lysosomal 功能障碍以破坏自流并促进中风后的神经炎症

Siyi Xu1,2, Pinyi Liu1,3,4,5, Junqiu Jia1

  • 1Department of Neurology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, Jiangsu, 210008, China.

Journal of neuroinflammation
|November 1, 2025
PubMed
概括

含有NOD类受体家族酶招募域的蛋白质5 (NLRC5) 通过损害 lysosomal 功能和促进神经炎症而加剧缺血性中风损伤. 针对NLRC5-ISG15途径为中风治疗提供了一个潜在的治疗策略.

关键词:
自自是一种自的过程.缺血性中风是因为缺血性中风.溶酶体功能障碍 溶酶体功能障碍微质细胞中的微质细胞在NLRC5中,NLRC5是NLRC5中的一个.

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