对疫苗的信心和对新型结核疫苗的潜在影响
Zsofia M Hesketh1,2, Rebecca A Clark3, Rupali Limaye4
1TB Modelling Group, TB Centre, Vaccine Centre, and Centre for Mathematical Modelling of Infectious Diseases, Department of Infectious Disease Epidemiology, LSHTM, London, UK. zsofia.hesketh@lshtm.ac.uk.
BMC global and public health
|November 1, 2025
概括
在引入新的结核病 (TB) 疫苗方面,对疫苗的普遍信心至关重要. 在高结核病负担的国家对2023年数据的分析确定了需要集中需求生成策略以改善疫苗准备的领域.
科学领域:
- 公共卫生 公共卫生
- 疫苗学 疫苗学 疫苗学
- 流行病学 流行病学
背景情况:
- 缺乏对疫苗的普遍信心,阻碍了新型结核病 (TB) 疫苗的推出.
- 在没有结核病特定调查的情况下,一般国家疫苗信心数据可以作为代理数据.
- 识别高结核病负担的国家与较低的疫苗信心是有针对性的干预的关键.
研究的目的:
- 通过2023年疫苗信心指数 (VCI) 数据,分析高结核病负担的国家对疫苗的一般信心.
- 确定可能需要针对未来结核病疫苗推广的专注需求生成策略的国家.
- 探索一般疫苗信心与结核病负担之间的关系.
主要方法:
- 分析了2023年来自18个高结核病负担国家的VCI数据 (占全球结核病负担的65%).
- 根据三个陈述,对"积极" (对疫苗有信心) 和"消极" (对疫苗犹) 的反应进行分类.
- 计算总疫苗置信度得分,使用阳性反应的平均比例.
主要成果:
- 在18个国家中,有14个国家的80%以上的受访者认为疫苗对所有年龄段的人都很重要.
- 印度,越南,埃塞俄比亚和塞拉利昂对疫苗的信心很高 (>90%).
- 南非,俄罗斯和喀麦隆对疫苗的信心较低 (<75.5%),这表明潜在的关注领域.
结论:
- 监测疫苗信心对于公众信任和解决疫苗接种挑战至关重要.
- 调查结果可以指导国家优先考虑社会动员和需求创造的努力.
- 提高对疫苗的信心可以提高对新的结核病疫苗的准备.
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