在无卵女性中与宏观症相关的不良周产期结局:一个多中心队列研究
Tzuria Peled1, Omer Ben Yishai2, Eliel Shapira1
1Department of Obstetrics and Gynecology, Faculty of Medicine, Shaare Zedek Medical Center, Hebrew University of Jerusalem, Jerusalem, Israel.
概括
无卵性妇女的巨显著增加了对孕产妇和新生儿不良结果的风险,包括肩膀缩和产后出血. 加强产前监测对于这些高风险怀孕至关重要.
科学领域:
- 产科和妇科 产科和妇科
- 孕产妇和胎儿医学 孕产妇和胎儿医学
- 新生儿科学 新生儿科学
背景情况:
- 无胎儿和胎儿巨是已知的怀孕的危险因素.
- 无性和宏观对分娩结果的综合影响需要进一步调查.
研究的目的:
- 评估胎儿巨与产后剖腹产 (CD) 的独立关联以及在无产妇妇女中产期分娩的不良孕妇和新生儿后果.
主要方法:
- 追溯性队列研究,对有期分娩的女性进行追溯性队列研究 (2005-2024).
- 妇女分娩宏观新生儿 (≥4000g) 与对照 (3000-3500g) 的比较.
- 多变量逻辑回归调整为混因子.
主要成果:
- 宏观症独立地与增加肩膀缩的几率,产后出血,输血,胸膜炎,新生儿急症监护室入院,新生儿低血糖症和Erb的/关节骨折有关.
- 观察到剂量与反应的关系,新生儿的并发症率最高>4500g.
- 虽然未经调整的产后CD率在宏观分娩中更高,但经过调整后,这种关联在统计学上并不显著.
结论:
- 胎儿巨独立地增加了许多不良的孕产妇和新生儿并发症的风险,在无胎妇女分娩到期.
- 调查结果强调,对于拥有宏观胎儿的无孕妇女来说,存在复合风险.
- 强调需要加强对这一群体的产前监测和个性化分娩计划.
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