双胞胎的产后结局基于胆性
Morgan C Kluge1, Loren Adler1, Lindsey T Ellis2
1Department of Medical Education, University of Missouri School of Medicine, Columbia, Missouri, USA.
概括
单胆双胞胎 (MoDi) 经历了更长的新生儿重症监护室 (NICU) 停留,需要比二胆双胞胎 (DiDi) 更多的非侵入性通风 (NIV). 这些结果与表性有关,而不是早产或出生体重.
科学领域:
- 新生儿医学 新生儿医学
- 周围生理学 周围生理学
- 双胞胎研究 双胞胎研究
背景情况:
- 胎盘和羊水囊的数量,可性,显著影响双胞胎怀孕的结果.
- 了解基于胆性的短期新生儿结果对于NICU护理至关重要.
研究的目的:
- 为了比较短期新生儿重症监护室 (NICU) 结局在单胆双胞胎 (MoDi) 和二胆双胞胎 (DiDi) 之间的结局.
- 确定胆管性是否是一个独立的因素,影响NICU停留时间 (LOS) 和非侵入性通风 (NIV) 持续时间.
主要方法:
- 在2015年至2023年期间被录取到NICU的双胞胎的回顾性分析.
- 在143个MoDi和149个DiDi双胞胎之间的LOS和NIV持续时间的比较.
- 线性回归和倾向匹配分析对妊娠年龄和出生体重进行控制.
主要成果:
- 与DiDi双胞胎相比,MoDi双胞胎的LOS和NIV持续时间明显更长 (分别为P=0.008和P=0.010).
- 线性回归证实胆管性作为决定因素,独立于妊娠年龄和出生体重.
- 倾向匹配分析证实了这些发现.
结论:
- 单胆双胞胎需要比二胆双胞胎更长的NICU停留时间和更多的非侵入性通风支持.
- 胆性是接受新生儿重症监护室治疗的双胞胎短期不良结果的重要独立预测因素.
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