评估乳腺癌风险评估和预防计划的实施和维护
Marybeth Hans1, Arya S Tamaskar1, Abigail Recko1
1Division of Breast Surgery, Department of Surgery, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Boston, MA, USA.
乳腺癌个性化风险评估,教育和预防 (B-PREP) 计划成功增加了高风险患者的化疗预防吸收. 计划成熟减少了启动时间,临床医生认为支持和评估是可持续性的关键.
科学领域:
- 在瘤学瘤学.
- 预防医学 预防医学
- 医疗保健服务研究 医疗服务研究
背景情况:
- 了解推动高风险乳腺健康计划成功的因素对于开发类似举措至关重要.
- 乳腺癌个性化风险评估,教育和预防 (B-PREP) 计划使用RE-AIM框架进行了评估.
研究的目的:
- 评估B-PREP计划的影响和可持续性.
- 评估该计划的覆盖范围,有效性,采用,实施和维护.
主要方法:
- 对2017年1月至2024年9月期间5972名患者的前性维护数据库的回顾性审查.
- 达到被测量为患者体积随时间的推移;通过化学预防吸收的有效性.
- 使用程序可持续性评估工具 (PSAT) 的临床医生和工作人员调查评估了实施和维护.
主要成果:
- 在5972名患者中,31.1%患有高风险病变 (HRL).
- 化疗预防启动率总体为7.38%,HRL患者 (22.5%) 与非HRL患者 (0.5%) 显著高.
- 持续的化疗预防 (≥6个月) 也在HRL患者 (15.4%) 中较高. PSAT评分表明可持续性很高 (6.13/7),特别是在适应,评估和环境支持方面.
结论:
- 该B-PREP计划有效地增加了每年化疗预防的使用量,并随着诊所成熟而减少了启动时间.
- 临床医生确定的关键可持续性因素包括支持性环境,定期的项目评估和适应性.
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