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评估数字治疗对男性LUTS的影响:来自BEST试验亚组分析的见解

Laura Wiemer^1,2, Christian Gratzke³, Kurt Miller^4,5

¹Department of Urology, Charité, Universitätsmedizin Berlin, Berlin, Germany. laura.wiemer@charite.de.

World journal of urology

|November 1, 2025

概括

一个数字健康应用程序有效地治疗了下尿道症状 (LUTS) 的男性,改善了不同患者群体的症状和生活质量. 观察到很高的坚持率.

科学领域:

泌尿器科泌尿器科泌尿器科泌尿器科
数字健康数字健康
男人的健康男人的健康

背景情况:

下泌尿道症状 (LUTS) 影响了一个异质的男性群体.
数字健康应用程序为管理男性LUTS提供了一种新的方法.
最好的试验评估了针对男性LUT的特定数字治疗方法.

研究的目的:

评估数字健康应用程序在LUTS的男性中的有效性.
根据临床特征进行子组分析.
报告排尿日记结果和坚持数据.

主要方法:

这是一项随机对照试验,涉及237名男性患者.
干预组接受了基于应用程序的治疗 (Kranus Lutera) 以及标准护理.
对照组仅接受标准护理.
主要终点:12周IPSS和OAB-qSF的变化.
根据诊断,症状严重程度,年龄和药物使用情况进行子组分析.

主要成果:

持续12周的改善有利于跨诊断的干预组 (IPSS差异 -6.4至 -7.4).
在严重的LUTS (-10.7) 中观察到的最大改善.
无论年龄或药物使用情况,都观察到好处.
减少白天/夜间空白的频率和紧急事件.
在干预组中,参与率为84%.

结论:

数字疗法为患有LUTS的男性提供了临床上有意义的症状和生活质量的改善.
在各种子组中,有效性是一致的.
减少排空频率和高粘附度支持广泛的临床应用.

关键词:

这是一种BPH.数字疗法是数字疗法.男的路特斯 (Luts) 是一个男的路特斯.这是OAB的OAB.小组子组分组子组.

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