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无管胰岛素与基于云的数据管理平台相结合:来自14765名法国糖尿病患者的现实世界证据
Nathalie Jeandidier1, Arthur Bagel2, Alice Bonin3
1Service d'Endocrinologie, Diabète, Nutrition, CHRU Strasbourg, Université de Strasbourg, Strasbourg, France.
概括
糖尿病的无管胰岛素使用者表现出适度的葡萄糖控制和良好的安全结果. 观察到持续的使用,这表明研究和改善患者护理的潜力.
科学领域:
- 内分泌学 在内分泌学.
- 代谢疾病 代谢疾病
- 医疗器械 医疗器械
背景情况:
- 检查儿童,青少年和成人1型 (T1D) 和2型糖尿病 (T2D) 的葡萄糖指标和胰岛素输送模式.
- 使用无管Omnipod DASH®胰岛素,通过myDiabby Healthcare®数据管理平台 (DMP) 集成连续血糖监测 (CGM).
研究的目的:
- 通过使用特定的胰岛素系统,分析大量糖尿病患者对葡萄糖控制和胰岛素输送的现实数据.
- 评估与CGM结合的无管胰岛素治疗相关的有效性和安全结果.
主要方法:
- 从DMP中提取了17344名用户的时间CGM和胰岛素数据,最初的数据是2020年1月1日之后的.
- 包括至少有90天的和CGM数据的用户,并在>15.5%的日内>70%的CGM覆盖率.
- 根据糖尿病类型 (T1D与T2D) 和年龄组进行了分层分析.
主要成果:
- 分析包括14,757名用户,主要是T1D (93.7%),平均年龄为33岁.
- 中位时间在范围 (TIR) 为T1D的52.5%和T2D的66.9%;12.6%的T1D和42.8%的T2D用户实现了TIR≥70%.
- 对于T1D使用者来说,中位时间低于范围 (TBR) 为3.7%;超过90%的所有用户每天消耗<60 IU.
结论:
- 无管胰岛素的使用者表现出中度的血糖结果和有利的安全概况.
- 在研究群体中观察到胰岛素系统的持续和持续使用.
- 像这个DMP这样的大型,高质量的数据库为糖尿病研究和临床实践优化提供了重要的价值.
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