在临床环境中对双重诊断患者概况进行系统审查和元分析
Hemant Choudhary1, Shubha Bagri1, Manish Roshan Thakur2
1Department of Psychiatry & National Drug Dependence Treatment Centre, All India Institute of Medical Sciences, New Delhi, India.
双重诊断,即精神健康和物质使用障碍的同时发生,在临床环境中非常普遍. 这项系统性审查发现,近一半的患者有双重诊断,突出了综合护理的必要性.
科学领域:
- 精神病学是一种精神病学.
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 双重诊断,其特点是精神健康障碍和物质使用障碍的同时发生,在临床环境中提出了重大挑战.
- 了解双重诊断的患病率对于有效的患者管理和资源分配至关重要.
研究的目的:
- 在各种临床环境中系统地审查和元分析双重诊断患者的比例.
- 在不同研究中识别导致双重诊断流行率变化的因素.
主要方法:
- 在MEDLINE和谷歌学者中进行了全面的文献搜索,截至2024年7月.
- 包括的研究是观察性,回顾性和队列设计,报告了双重诊断比例.
- 进行了随机效应元分析,偏差风险评估和子组分析.
主要成果:
- 分析包括32项研究,累计样本大小为2,805,009名患者.
- 在研究中观察到高程度的异质性,在子组分析中持续存在.
- 双重诊断的综合比例为44.70% (95% CI,0.28-0.63),中位数为47.90%.
结论:
- 双重诊断在临床环境中非常普遍,因环境,评估方法和国家而有很大的变化.
- 这些发现强调,迫切需要进一步研究和针对双重诊断患者的综合管理策略.
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