大脑-肠-微生物群轴:腹部针治疗的有效目标,用于中风后功能性便秘
Sicheng Li1, Shengjie Wang1, Sisi Li2
1Department of Rehabilitation, Hubei Provincial Hospital of Integrated Chinese and Western Medicine, Hubei University of Chinese Medicine, Wuhan, China.
Complementary therapies in medicine
|November 1, 2025
概括
腹部针 (AA) 通过改善肠道微生物群和神经功能,有效地治疗中风幸存者的功能性便秘. 这种方法为改善中风后的康复和生活质量提供了一个有希望的策略.
科学领域:
- 综合医学是一个整体的医学.
- 神经康复疗法 神经康复疗法
- 胃肠病学 胃肠病学
背景情况:
- 功能性便秘是中风患者常见的并发症,严重影响他们的生活质量.
- 大脑-肠-微生物群轴与中风后功能性便秘有关.
- 这项研究研究了腹部针在治疗这种疾病中的作用.
研究的目的:
- 评估腹部针 (AA) 在治疗中风后患者功能性便秘的疗效.
- 评估AA对肠道微生物群组成的影响.
- 确定AA对神经功能和残疾率的影响.
主要方法:
- 75名患有功能性便秘的中风后患者随机分为腹部针 (AA) 或常规治疗 (RT) 组.
- 两组都接受了标准的中风护理;AA组额外接受了腹部针.
- 测量结果包括便秘得分,便菌群,NIHSS,FMA,MBI,LOS和静止状态fNIRS.
主要成果:
- 两组都表现出改善,但AA组在便秘,神经功能 (NIHSS,FMA,MBI,LOS) 和皮质活动方面表现出明显更大的改善.
- 腹部针调节了肠道微生物群,减少了大肠杆菌和肠杆菌,同时增加了Bifidobacterium,Lactobacillus和Bacteroides.
- 在治疗后的各组之间观察到皮质功能活动的显著差异.
结论:
- 腹部针有效缓解中风后的功能性便秘.
- AA对肠道微生物群产生积极影响,并增强中风幸存者的神经功能.
- AA可以降低残疾率,并改善中风后患者的整体预后.
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