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相关概念视频

Bone Remodeling01:40

Bone Remodeling

Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.

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Reduced paraspinal muscle endurance and electromyographic fatigability are associated with greater global spinal imbalance in symptomatic lumbar spinal stenosis.

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DXA-derived biofidelic finite element models for quantifying the efficacy of hip protectors.

JBMR plus·2026
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Characterization of the acetabular labrum articular surface and its translation into biomimetic graft design.

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相关实验视频

Updated: Jun 7, 2026

Computed Tomography and Optical Imaging of Osteogenesis-angiogenesis Coupling to Assess Integration of Cranial Bone Autografts and Allografts
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用户定义的元素模拟水凝注射到椎骨:数值模拟和实验验证验.

Georgios F Samaras1, Vincent Dischl1, Anita Fung1

  • 1Institute for Biomechanics, ETH Zürich, Zürich, Switzerland.

Medical engineering & physics
|November 1, 2025
PubMed
概括

这项研究开发了一种数值模型来模拟在股骨中注射水凝,准确地预测骨增大模式. 该模型有助于为骨质疏松症患者制定更安全的治疗计划.

关键词:
在 Abaqus 用户元素中使用 Abaqus.结合的多物理学.骨质疏松症是一种骨质疏松症.孔隙介质理论 孔隙介质理论

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科学领域:

  • 生物力学 生物力学
  • 生物材料工程 生物材料工程
  • 计算机建模 计算建模

背景情况:

  • 水凝注射是一种有前途的骨增强技术.
  • 精确模拟水凝与骨相互作用对于治疗规划至关重要.
  • 现有的模型可能无法完全捕捉到所涉及的复杂生物机械和风湿学因素.

研究的目的:

  • 开发和验证一个全面的数值模型来模拟在股骨内注射水凝.
  • 研究水凝特性和注射参数对增强模式的影响.
  • 通过量化骨干菌株来评估注射过程的安全性.

主要方法:

  • 基于孔状介质理论的合机械流量配方被实施.
  • 该模型是作为一个开源的Abaqus用户元素 (UEL) 子程序开发的.
  • 水凝的质性质与来自三个股骨的实验数据进行校准.

主要成果:

  • 该模型准确地预测了水凝体积分布,平均子系数为0.75.
  • 模拟揭示了注射流速和骨透度对水凝模式的影响.
  • 计算的固体应变在测试的流速范围内仍低于拉力收益率极限.

结论:

  • 开发的计算工具提高了骨增强建模的准确性.
  • 这种方法可以为骨质疏松患者的更安全的治疗计划做出贡献.
  • 该模型提供了关于注射期间水凝与骨相互作用的见解.