在澳大利亚社区样本中,患者报告了睡眠呼吸暂停治疗的偏好
Julia E Stone1, Simon A Joosten2, Caroline Beatty3
1Melbourne School of Psychological Sciences, The University of Melbourne, Parkville, VIC, Australia.
Sleep health
|November 1, 2025
概括
患有阻塞性睡眠呼吸暂停 (OSA) 的患者更喜欢药物或鼻喷雾剂而不是CPAP,MAS或手术. 副作用显著影响治疗的可接受性,头痛和恶心是最有害的.
科学领域:
- 睡眠医学 睡眠医学
- 呼吸系统医学 呼吸系统医学
- 药理学 药理学是指药理学的学科.
背景情况:
- 患者的偏好对于长期坚持阻塞性睡眠呼吸暂停 (OSA) 治疗至关重要.
- 了解这些偏好是改善治疗结果的关键.
研究的目的:
- 在澳大利亚社区样本中评估患者对各种阻塞性睡眠呼吸暂停 (OSA) 治疗选择的偏好.
- 评估副作用对治疗可接受性的影响.
主要方法:
- 一项在线调查对948名澳大利亚成年人进行,他们被诊断患有OSA.
- 参与者使用视觉模拟秤评价了持续正气道压力 (CPAP),下前进 (MAS),手术和药物治疗 (口服药物,鼻喷雾) 的可接受性.
- 研究了副作用对药物治疗可接受性的影响.
主要成果:
- 药物治疗 (口服药物或鼻喷雾) 被评为最可接受的OSA治疗 (中位数86),明显高于CPAP (73),MAS (50) 和手术 (50).
- 超过58%的受访者认为药物比CPAP更可接受,而72%的人更喜欢它.
- 在女性,非肥胖个体和伴随性失眠患者中,CPAP的可接受性较低. 像头痛和恶心这样的副作用对接受度产生了负面影响,而夜间嗜睡是可以容忍的.
结论:
- 澳大利亚的OSA患者显然更喜欢药物或鼻喷雾替代品.
- 药物治疗的耐受性受到药物治疗的副作用特征的显著影响.
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