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使用人体脂肪合种植物的脂肪增强可以在固的脚部中产生持久的闭合

Kristen McGinness¹, Brad Peck¹, Usman Javed¹

¹Cape Fear Valley Podiatry, Fayetteville, NC, USA.

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概括

人类冷保存脂肪组织全移植 (hCAT) 在与标准护理一起使用时,有效地帮助慢性脚下的愈合. 这种治疗显示出高关闭率和没有不良事件,为反抗性提供了一个有希望的解决方案.

科学领域:

再生医学是一种再生医学.
伤口愈合治愈伤口愈合
组织工程是组织工程.

背景情况:

慢性脚下通常是由脂肪缩引起的,导致高血压.
目前的标准护理 (SOC) 仅提供暂时的缓解,而不解决脂肪缺陷的根本原因.

研究的目的:

为了评估人体冷保存脂肪组织全移植 (hCAT) 与SOC相结合的手术内治疗慢性复发性脚下的疗效.
评估关闭率,关闭时间,无持续时间和与hCAT相关的不良事件.

主要方法:

一个回顾性病例系列包括八名患有长期脚下和重大并发症的患者.
患者接受了手术脱bridement,随后hCAT植入和SOC.
测量结果包括完全关闭,关闭时间,无状态的持续时间和hCAT相关的不良事件.

主要成果:

87.5%的患者在平均2.8个月内实现了的完全关闭.
在分析时,关闭后没有的平均持续时间为5.6个月.
没有报告hCAT相关的不良事件.

结论:

人类冷保存脂肪组织全移植 (hCAT) 作为一种有效的标准护理补充剂,用于管理慢性反复性脚下.
hCAT表现出良好的安全性,并促进了明显的伤口愈合.

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