不同功能组对烯衍生物对Skeletonema costatum的毒性的影响:与聚烯微塑料的相互作用作用
Yangzhi Liu1, Qilu Wang2, Qilu Cheng1
1State Key Laboratory for Quality and Safety of Agro-Products, Institute of Environment, Resource, Soil and Fertilizers, Zhejiang Academy of Agricultural Sciences, Hangzhou, 310021, China.
Marine pollution bulletin
|November 2, 2025
概括
替代多环芳 (S-PAHs) 对海洋藻具有不同的毒性,微塑料可能会降低这些风险. 分子分析揭示了在联合污染物压力下对代谢途径的影响.
科学领域:
- 海洋生态毒理学 海洋生态毒理学
- 环境化学环境化学
- 分子生物学分子生物学
背景情况:
- 多环芳 (PAH) 和微塑料是持续性海洋污染物.
- 替代PAHs (S-PAHs) 的毒性和微塑料与微藻的相互作用是不太了解的.
研究的目的:
- 研究烯及其衍生物 (S-Pyr) 对海洋藻 (Skeletonema costatum) 的毒性.
- 评估聚烯微塑料 (微PS) 对S-PAH毒性的影响.
- 阐明S-PAH和微塑料暴露的分子反应.
主要方法:
- Skeletonema costatum对烯,S-Pyr和微PS的暴露.
- 评估生理指数 (生长,光合作用,氧化应激标志物).
- 转录组分析以确定差异表达的基因.
主要成果:
- S-PAH衍生物 (1-甲基烯,1-氧烯,1-氨基烯) 的毒性高于烯,而1-烯碳酸的毒性较低.
- 微PS减轻了pyrene和S-Pyr对S. costatum的毒性.
- 联合暴露导致基因表达的差异比单次暴露更大,主要影响代谢途径.
结论:
- 替代的PAH对海洋微藻有不同的风险.
- 微塑料可以调节S-PAHs的生态毒性.
- 了解这些相互作用对于评估海洋生态系统风险至关重要.
相关概念视频
Radical Reactivity: Steric Effects
2.4K
The presence of electron-donating, electron-withdrawing, or conjugating groups adjacent to a radical center, imparts electronic stabilization to the radicals. Examples of such electronically-stabilized radicals are triphenylmethyl, tetramethylpiperidine‐N‐oxide, and 2,2‐diphenyl‐1‐picrylhydrazyl. These radicals are remarkably stable and are known as persistent radicals. Some of the persistent radicals can even be isolated and purified.
Along with electronic...
Along with electronic...
2.4K
Toxic Reactions: Overview
1.8K
When toxic substances penetrate the human body, they disseminate to various tissues, undergoing metabolic changes. This process yields reactive metabolites that may covalently bind with specific target molecules, resulting in toxicity.
Toxicity falls into two primary categories: local and systemic.
Local toxicity appears at the exposure site, such as protein denaturation caused by caustic substances.
In contrast, systemic toxicity requires the toxic agent's absorption and distribution,...
Toxicity falls into two primary categories: local and systemic.
Local toxicity appears at the exposure site, such as protein denaturation caused by caustic substances.
In contrast, systemic toxicity requires the toxic agent's absorption and distribution,...
1.8K
Polymer Classification: Stereospecificity
3.1K
Polymerization generates chiral centers along the entire backbone of a polymer chain. Accordingly, the stereochemistry of the substituent group has a significant effect on polymer properties. Polymers formed from monosubstituted alkene monomers feature chiral carbons at every alternate position in the polymer backbone. Relative to the predominant orientation of substituents at the adjacent chiral carbons, the polymer can exist in three different configurations: isotactic, syndiotactic, and...
3.1K


