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肠球菌 (Enterococcus spp.) 是一种细菌. 形成干燥表面生物膜的能力:在环境表面持久的途径

R Harsent¹, V Cattoir², M Pascoe¹

¹School of Pharmacy and Pharmaceutical Sciences, Cardiff University, Cardiff, UK.

The Journal of hospital infection

|November 2, 2025

概括

菌种在医疗保健表面形成持久的干表面生物膜 (DSB),持续超过84周. 加强清洁和消毒目前是控制这些有弹性的病原体库的最佳方法.

科学领域:

微生物学微生物学
传染性疾病传染性疾病
环境健康环境健康

背景情况:

与医疗保健相关的感染 (HAI) 是一个主要的全球健康问题,由抗药多种生物体 (如抗万科胺素的肠球菌 (VRE)) 加剧.
干表面生物膜 (DSBs) 是医疗保健机构中病原体的新兴储存库,但它们的形成和由肠球菌的持久性尚不清楚.

研究的目的:

调查各种Enterococcus物种在常见的医疗保健材料上形成DSB的能力.
评估这些肠球菌DSBs的长期生存能力和培养能力.
探索影响DSB形成和持久性的因素.

主要方法:

一个标准化的DSB模型被用来在各种医疗保健表面培养多个肠球菌菌株,包括VRE.
培养能力是通过连续稀释和殖民地数量来确定的.
扫描电子显微镜 (SEM),共聚焦显微镜和流细胞计用于结构和可行性分析.

主要成果:

所有测试的肠球菌株都成功地在不钢和其他临床材料上形成了DSB.
在受控条件下 (20°C,55%RH),DSB在长达84周的时间内保持高度可培养.
与非VRE菌株相比,VRE菌株的培养能力降低;DSB形成和表面特性之间没有发现相关性.

结论:

菌种在各种医疗保健表面形成持久且可行的DSB,有助于病原体的环境持久性.
机械去除与有效消毒相结合,是目前控制硬表面肠球菌DSB的最佳策略.

关键词:

在DSB中,DSB是DSB.肠球菌 (Enterococcus) 是一个细菌.坚持不坚持不表面上的表面.可行性可行性.

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