激素治疗后跨性别青少年自杀倾向的变化:一项扩展研究
Luke R Allen1, Cody G Dodd2, Christine N Moser3
1Independent Practice, Las Vegas, NV.
The Journal of pediatrics
|November 2, 2025
概括
激素治疗 (HT) 在跨性别和性别多元青年中显著降低了自杀倾向. 这一发现支持及时获得性别确认护理,以改善心理健康结果.
科学领域:
- 内分泌学 在内分泌学.
- 精神病学是一个精神病学.
- 青少年医学 青少年医学
背景情况:
- 跨性别和性别多元 (TGD) 的青少年和年轻人经历了不成比例的高自杀率.
- 激素治疗 (HT) 是性别肯定护理的关键组成部分,但它对自杀倾向的影响需要进一步调查.
研究的目的:
- 研究激素治疗 (HT) 与TGD个体中自杀倾向的变化之间的纵向关联.
- 提供关于HT对TGD年轻人的心理健康益处的临床证据.
主要方法:
- 在性别健康诊所对432名TGD患者的回顾性图表审查.
- 使用问自杀查问题 (ASQ) 工具在治疗前后进行治疗.
- 反复测量ANCOVA分析了人体内自杀倾向的变化,控制共变量.
主要成果:
- 从治疗前到治疗后观察到自杀倾向的统计显著下降 (P < .001).
- 自杀倾向的减少在出生时分配的不同性别,治疗开始时的年龄和治疗持续时间之间是一致的.
- 效果大小 (部分 η2 = 0.075) 表明临床上有意义的影响.
结论:
- 激素治疗与TGD青少年和年轻成年人中自杀倾向的显著和临床上有意义的减少有关.
- 这些发现强化了及时获得性别肯定激素疗法的重要性,以改善这一群体的心理健康结果.
- 该研究提供了强有力的临床证据,支持将HT纳入全面的TGD医疗保健.
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