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Updated: Jan 12, 2026

Suppression of Pro-fibrotic Signaling Potentiates Factor-mediated Reprogramming of Mouse Embryonic Fibroblasts into Induced Cardiomyocytes
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IGF-1促进HCN4心脏起器通道的细胞表面表达,有助于高心率

Nadine Erlenhardt1, Franziska Wohlfarth1, S Erfan Moussavi-Torshizi1

  • 1Institute of Neural and Sensory Physiology, Medical Faculty and University Hospital, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.

Journal of molecular and cellular cardiology
|November 2, 2025
PubMed
概括

胰岛素类生长因子1 (IGF-1) 通过增加HCN4通道的表面表达来加速心脏节拍. 这一发现揭示了IGF-1的特征.

关键词:
细胞内循环回收区的内细胞回收.细胞外表位标记的标记超极化激活的循环核酸封闭离子通道.胰岛素类生长因子-1光学映射绘制的光学映射.亚细胞贩运活动

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