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Updated: Jan 12, 2026

Mechanistic Insight into the Development of TNBS-Mediated Intestinal Fibrosis and Evaluating the Inhibitory Effects of Rapamycin
10:21

Mechanistic Insight into the Development of TNBS-Mediated Intestinal Fibrosis and Evaluating the Inhibitory Effects of Rapamycin

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内在的微RNA-10a通过协调转录,代谢和上皮细胞修复途径来限制调节性T细胞抑制功能和肠道修复

Wenjing Yang1,2,3, Tianming Yu1,2,3, Hui Yang3

  • 1Division of Gastroenterology and Hepatology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|November 3, 2025
PubMed
概括

微RNA-10a抑制了调节性T细胞 (Treg) 功能,影响了免疫平衡. 它的缺乏增强了Treg抑制能力和肠道屏障修复,为炎症性肠道疾病提供了潜在的治疗点.

关键词:
肠道炎症是一种肠道炎症.肠道修复 肠道修复这是一个微型RNA.线粒体中的线粒体.氧化酸化是一种氧化酸化.

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