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Shojiro Haji, Yoshihiro Ogawa

    The Journal of clinical investigation
    |November 3, 2025
    PubMed
    概括

    研究人员确定了致病性巨细胞,称为Toe-Macs,在MASH和NSCLC等慢性炎症性疾病中过度表达TET3. 选择性消除这些Toe-Macs可以减少疾病的进展,这表明TET3是潜在的治疗点.

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