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开发和验证一种营养素养评估尺度,用于同时接受化疗或放射治疗的鼻癌患者
Zhang Yanxin1, Huang Xiaojun1, Yang Guirong1
1Department of Radiotherapy, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Frontiers in nutrition
|November 3, 2025
概括
一个新的营养素质量表 (NLS) 已经开发用于鼻癌 (NPC) 患者接受化疗和放射治疗. 该尺度表现出良好的可靠性和有效性,有助于优化NPC患者的营养管理.
科学领域:
- 在瘤学瘤学.
- 营养科学 营养科学
- 卫生识字 卫生识字
背景情况:
- 鼻癌 (NPC) 是东亚/东南亚的一个普遍的头癌.
- 同时化学辐射疗法 (CCRT) 是标准治疗,但会导致严重的毒性.
- 营养状况受到治疗副作用,患者知识不足和饮食误解的影响.
研究的目的:
- 开发和验证适用于接受CCRT的NPC患者的营养素养量表 (NLS).
- 加强对接受CCRT的NPC患者的营养管理策略.
- 通过优化营养支持来改善治疗结果.
主要方法:
- 该尺度是使用文献分析,半结构面试和专家通信开发的.
- 在2024年4月至12月期间,招募了245名接受CCRT的NPC患者.
- 进行了项目分析,可靠性和有效性测试,包括两周后重新测试.
主要成果:
- 最终的NLS包括4个维度和30个项目.
- 探索和验证的因子分析证实了尺度的结构 (累计方差为62.3%).
- 该尺度表现出卓越的可靠性 (克朗巴赫α 0.849,重新测试 0.960) 和有效性 (S-CVI 0.932).
结论:
- 为接受同时放射治疗的鼻癌患者开发的营养素质量表显示出强大的可靠性和有效性.
- 这种经过验证的尺度是评估和改善接受CCRT的NPC患者的营养素质识别的宝贵工具.
- 通过这种量表来优化营养管理可能会提高治疗疗效和患者的治疗结果.
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