在COVID-19中甲状腺功能障碍的流行和演变:一项回顾性研究
Shourya Tadisina1, Sobrina Mohammed1, Reda Asad1
1Endocrinology, Diabetes and Metabolism, University of Missouri - Kansas City, Kansas City, USA.
Cureus
|November 3, 2025
概括
甲状腺功能障碍,包括亚临床甲状腺功能低下症和非甲状腺疾病综合征,影响超过13%的COVID-19患者. 这些甲状腺问题通常是暂时的,并没有恶化而消失,这表明有症状的个体需要监测.
科学领域:
- 内分泌学 在内分泌学.
- 传染性疾病 传染性疾病
- 内部医学 内部医学
背景情况:
- COVID-19主要影响呼吸系统,但也影响内分泌功能.
- 甲状腺功能障碍与COVID-19有关,关于其在疾病严重性中的作用的争论正在进行中.
- 了解COVID-19中甲状腺功能障碍的患病率和过程对于患者管理至关重要.
研究的目的:
- 确定甲状腺功能障碍在已确诊COVID-19的成年患者中的患病率和演变.
- 为了确定在COVID-19患者中最常见的甲状腺异常类型.
- 为了评估甲状腺功能障碍是否在COVID-19感染后的患者中进展.
主要方法:
- 一项对615名成年COVID-19患者进行甲状腺功能测试的回顾性研究.
- 排除具有先前存在的甲状腺疾病或影响甲状腺的药物患者.
- 使用SPSS进行统计分析,以比较甲状腺功能测试异常.
主要成果:
- 甲状腺功能障碍存在于13.6%的患者中 (615人中84人).
- 最常见的发现包括非甲状腺疾病综合征 (46.4%) 和亚临床甲状腺功能低下症 (44%).
- 在一年的随访期间,甲状腺功能障碍通常不会发展为明显的疾病.
结论:
- 甲状腺功能障碍是COVID-19患者的显著并发症,特别是亚临床甲状腺功能低下症和NTIS.
- 这些甲状腺异常往往是暂时的,自我限制.
- 病变发生可能涉及病毒和炎症机制;由于与长期COVID症状重叠,建议对症状患者的甲状腺功能进行监测.
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