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Updated: Jan 12, 2026

Characterizing Mutational Load and Clonal Composition of Human Blood
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Characterizing Mutational Load and Clonal Composition of Human Blood

Published on: July 11, 2019

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单细胞无倍积分和染色体臂不平衡定义了具有不同转录体表型的亚克隆

Xiangqi Bai1, Billy T Lau1, Anuja Sathe1

  • 1Division of Oncology, Department of Medicine, Stanford University School of Medicine, Stanford, CA94305, United States.

NAR genomics and bioinformatics
|November 3, 2025
PubMed
概括

我们开发了scAlign,这是一个计算框架,用于整合单细胞RNA和DNA测序数据. 这种方法定义了癌细胞表型,并通过分析亚克隆结构来揭示内异质性.

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