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验证GPSS问卷对查阻塞性睡眠呼吸暂停的有效性

Zhuoji Li¹, Hanyue Liu¹, Wang Liu¹

¹The Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China.

Frontiers in medicine

|November 3, 2025

概括

一般实践睡眠量表 (GPSS) 显示了对轻度至中度阻塞性睡眠呼吸暂停 (OSA) 的查的希望,在某些情况下,其表现优于其他工具. 检测严重的OSA需要进一步细化,建议与其他方法结合使用.

科学领域:

睡眠医学睡眠医学
呼吸系统医学呼吸系统医学
诊断工具开发诊断工具开发

背景情况:

阻塞性睡眠呼吸暂停 (OSA) 是一种普遍的疾病,需要有效的查工具.
现有的查问卷在临床适用性和性能上因OSA严重程度而有所不同.
一般实践睡眠量表 (GPSS) 是一种新开发的用于OSA查的问卷.

研究的目的:

将GPSS的选性能与四个已建立的问卷 (NoSAS,柏林,STOP,STOP-Bang) 进行比较.
为了评估这些问卷的诊断准确性,跨越不同级别的OSA严重程度.
评估GPSS在识别阻塞性睡眠呼吸暂停患者中的临床适用性.

主要方法:

从一个睡眠中心的2,169名患者和另一个睡眠中心的310名患者的回顾性分析.
计算每个调查问卷的灵敏度,特异性,正预测值 (PPV),负预测值 (NPV) 和曲线下的面积 (AUC).
对所有OSA患者和中度/重度OSA患者的查性能进行比较.

主要成果:

在一个队列中的所有OSA患者中,GPSS表现出更高的特异性和PPV.
在第二组中,GPSS显示所有OSA患者的灵敏度,PPV和NPV都更高,而中度/重度OSA患者的特异性和PPV更高.
ROC分析表明,GPSS在查轻度至中度OSA方面具有优势,AUC在不同患者组和队列中从0.69到0.77不等.

结论:

GPSS对于选轻度至中度阻塞性睡眠呼吸暂停 (OSA) 有效.
虽然有希望,但GPSS需要改进,以检测严重的OSA.
建议GPSS用于早期的OSA查,特别是在初级保健中;考虑在高风险的严重OSA患者中联合使用.

关键词:

在GPSS问卷上使用.没有SASAS.在STOP-bang中使用STOP.诊断疗效诊断疗效诊断疗效阻塞性睡眠呼吸暂停 (SOP) 的情况.

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