超声波表征表面淋巴结在艾滋病毒患者的淋巴腺病变的表面淋巴结

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Lin Pan¹, Hong Liu², Huaguo Shao³

¹Department of Ultrasound, Hangzhou Xixi Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou City, Zhejiang Province, China.

Frontiers in medicine

|November 3, 2025

概括

超声波和T细胞分析有助于在HIV患者中区分良性和恶性淋巴结. CD4+T细胞比率是恶性瘤的关键指标,有助于诊断.

科学领域:

医学成像医学成像
免疫学免疫学免疫学
在瘤学瘤学.

背景情况:

艾滋病毒感染导致免疫缺陷和机会性感染,经常出现淋巴腺病.
表面淋巴腺病在人类免疫缺陷病毒 (HIV) 患者中很常见,需要区分良性和恶性原因.
准确的区分对于适当的患者管理和治疗策略至关重要.

研究的目的:

用超声波对艾滋病毒患者的表面淋巴结特征进行表征.
为了将超声波发现与T细胞子集数据相关联.
在HIV感染个体中区分良性和恶性淋巴结核病.

主要方法:

149名患有淋巴腺病的艾滋病毒患者的回顾性观察研究 (2016年3月至2024年3月).
表面淋巴结的超声波检查.
通过活检和统计分析 (包括后勤回归) 来确认病理.

主要成果:

恶性淋巴结呈现出更大的尺寸,较低的长短轴 (L/S) 比率,缺席的,在超声波上呈现出低声的外观.
恶性群体的淋巴细胞,T细胞和CD4+T细胞数量较高.
CD4+ T细胞比率成为恶性瘤的独立预测因子 (OR 1.116,95% CI 1.003-1.247,p=0.043).

结论:

结合超声波和T细胞子集分析可以帮助在艾滋病毒患者中区分良性和恶性淋巴结核病.
在这个队列中,CD4+T细胞比率是恶性瘤的重要独立预测指标.
这种综合方法可以提高艾滋病毒感染个体淋巴结异常的诊断准确度.

关键词:

艾滋病病毒艾滋病病毒艾滋病病毒 T细胞子集是T细胞的子集.诊断诊断诊断诊断诊断诊断淋巴结的淋巴结是指淋巴结的超声波超声波是指超声波的使用.

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