在第三级医院设置中,在全血献血者中探索献血不良反应:一中心观察混合方法研究
Redeemer Nana Fabea Addae1, Patience Sobre1, Inusah Abdul Mumin1
1Department of Medical Laboratory Sciences, School of Allied Health Sciences, University of Cape Coast, Cape Coast, Ghana, ucc.edu.gh.
Advances in hematology
|November 3, 2025
概括
献血不良反应很常见,直接影响到44.4%的献血者,血管血管反应是最常见的. 年轻的捐赠者和体重或血压较低的人经历了更多的反应,突出了改善捐赠者护理协议的需要.
科学领域:
- 输血医学 输血医学
- 公共卫生 公共卫生
- 临床研究 临床研究
背景情况:
- 献血至关重要,但与不良反应相关,影响捐赠者回报.
- 关于加纳献血不良反应和危险因素的数据有限.
- 了解这些反应对于捐赠者的安全和保留至关重要.
研究的目的:
- 为了确定献血不良反应的患病率.
- 在成功捐赠者中识别与这些反应相关的风险因素.
- 为加纳的三级医院提供特定背景数据.
主要方法:
- 混合方法方法结合了观察技术和半结构化问卷.
- 279名参与者 (移动和内部捐赠者) 在第三级环境中招募.
- 用于评估对不良反应的人口影响的双变物流回归分析.
主要成果:
- 立即不良反应的患病率为44.4%,局部,血管和过敏反应分别为51.4%,36.5%和12.1%.
- 经历不良事件的捐赠者平均年龄,静脉血压,透气血压和体重显著降低.
- 22.1%的反应持续了捐赠后24小时;局部和血管反应是最常见的.
结论:
- 立即不良反应的高患病率需要改善捐赠者护理.
- 迫切需要提高工作人员的能力,并标准化管理不良事件的协议.
- 需要进一步的研究来了解促成因素,并为更好的献血者安全提供干预信息.
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