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Updated: Jan 12, 2026

An Appetitive Spatial Working Memory Task for Mice in a Semi-Automated 8-Arm Radial Maze, Reducing Fearful Memory Association in the Maze
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认知丰富改善空间记忆,并改变海马突触连接在小鼠模型的早期生活压力

Justin L Shobe1, Elham Ghanbarian1, Robert Bain1

  • 1Department of Neurobiology and Behavior, University of California, Irvine, CA, United States.

Frontiers in cellular neuroscience
|November 3, 2025
PubMed
概括

认知丰富逆转了小鼠在早期生活中的压力诱导的空间记忆缺陷. 这种干预改变了海马突触结构,为与压力相关的认知障碍提供了潜在的治疗途径.

关键词:
行为行为行为行为行为.早期的生活压力和的纤维纤维通过缩进行缩.在海马体内,海马体记忆 记忆 记忆 记忆 记忆突触性可塑性 突触性可塑性

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Role of Hippocampus in Memory01:19

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The hippocampus, a critical brain structure, plays an essential role in memory processing, particularly in the formation and retrieval of memory. This small, seahorse-shaped region is located within the medial temporal lobe, with one hippocampus in each brain hemisphere. Experimental studies involving lesions in the hippocampi of rats have demonstrated significant impairments in tasks such as object recognition and maze navigation, indicating the hippocampus involvement in both recognition and...
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