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Updated: Jan 12, 2026

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing
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Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing

Published on: October 15, 2019

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肠道微生物组和脊椎骨关节病的元基因组分析:一个系统的审查

Madhan Jeyaraman1,2,3,4, Easwar Balasubramanian5, Naveen Jeyaraman1,2,6

  • 1Department of Orthopaedics, ACS Medical College and Hospital, Dr MGR Educational and Research Institute, Chennai 600077, Tamil Nadu, India.

World journal of orthopedics
|November 3, 2025
PubMed
概括

由致病性细菌和病毒为特征的肠道失生症与脊椎关节炎 (SpA) 有关. 针对这些微生物可能为SpA和肠道健康提供新的治疗途径.

关键词:
化性关节炎是一种关节炎.我们的肠道微生物组.大基因组测序的测序.脊椎关节炎是一种脊柱性关节炎.

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Genome-wide Association Studies-GWAS01:11

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Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
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The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
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