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自主干细胞移植中的二甲基硫氧化物相关性厌恶症:一个案例报告

Didar Yanardag Acik¹, Elif Suyani¹, Bilal Aygun²

¹Department of Internal Medicine and Haematology, Faculty of Medicine, Health Sciences University Adana, Adana, Türkiye.

Case reports in medicine

|November 3, 2025

概括

甲基硫氧化物 (DMSO) 是血液细胞干细胞的常见冷保护剂. 本报告详细介绍了一例罕见的DMSO注射后急性过敏反应病例及其成功管理.

科学领域:

血液学血液学血液学
免疫学免疫学免疫学
药理学药理学是指药理学的学科.

背景情况:

甲基二硫氧化物 (DMSO) 广泛用于血造干细胞 (HSC) 的冷保存.
虽然DMSO通常被认为是安全的,但很少引起不良反应,包括过敏反应.
了解这些风险对于干细胞移植过程中的患者安全至关重要.

研究的目的:

在接受HSC冷保存的患者中,报告DMSO给药后发生的急性过敏反应病例.
描述这种罕见但严重的不良事件的临床表现和管理.
强调识别和及时治疗DMSO诱导的过敏反应的重要性.

主要方法:

一个在DMSO暴露后出现过敏反应的患者的病例报告.
对临床表现,诊断发现和治疗干预措施的审查.
讨论与DMSO过敏相关的病理生理学和危险因素.

主要成果:

患者在接受DMSO后不久就出现了急性过敏反应,以[特定症状]为特征.
[特定治疗]的迅速使用导致过敏反应症状迅速消失.
患者的病情稳定,没有观察到长期的后果.

结论:

急性过敏反应是一种罕见的,但在HSC冷保存中使用DMSO的潜在并发症.
及时识别和适当的医疗管理对于DMSO诱导的过敏反应的良好结果至关重要.
这一案例强调了在临床实践中对DMSO相关的过敏反应需要保持警.

关键词:

二甲基硫化物二甲基硫化物输入管道是输入管道的方法.危及生命的过敏反应过敏.管理的管理管理的管理.干细胞移植干细胞移植

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