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Updated: Jan 12, 2026

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B4GALT1和Wntless合作阻止LRP5/6从Golgi转移到细胞表面的转移

Xinyang Li1, Yue Hua2, Jiahui Wang1

  • 1Department of Biochemistry and Molecular Biology, Key Laboratory of Metabolism and Molecular Medicine, Ministry of Education, School of Basic Medical Sciences, Fudan University, Shanghai, PR China.

The Journal of cell biology
|November 3, 2025
PubMed
概括

戈尔吉酶B4GALT1保留了戈尔吉细胞中的LRP5/6共受体,减少了它们在细胞表面的存在. Wnt分泌活动抵消了这种保留,影响了LRP5/6细胞表面呈现.

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