用抗氧化剂治疗缓解剂治疗亚托皮炎:叙事性审查和共识陈述
Marco Hok Kung Ho1, Yung Chan2, Patrick Chun Yin Chong3
1Department of Paediatrics and Adolescent Medicine, School of Clinical Medicine, The University of Hong Kong, Hong Kong SAR, China.
Asian Pacific journal of allergy and immunology
|November 3, 2025
概括
治疗软化剂,包括抗氧化剂,为管理亚托皮炎 (AD) 症状和改善生活质量提供了新的希望. 这些专门的保湿剂可能有助于克服在AD护理中的类固醇恐惧症等挑战.
科学领域:
- 皮肤病学 皮肤病学
- 临床研究 临床研究
- 皮肤屏障科学 皮肤屏障科学
背景情况:
- 亚托邦性皮肤炎 (AD) 是一种普遍的炎症性皮肤疾病,严重影响患者的生活质量,特别是在亚洲.
- 在AD管理中的挑战包括公众的误解,对局部皮质类固醇 (TCS) 的恐惧,以及影响治疗坚持的湿度等环境因素.
- 软化剂在阿尔茨海默病治疗中对于皮肤水分和屏障修复至关重要.
研究的目的:
- 总结香港专家在临床AD管理方面的专家共识,强调软化剂的作用.
- 探索"治疗软化剂"的实用性 - - 那些具有活性,非药物,疾病向成分的药物 - - 用于临床实践和沟通.
- 评估治疗软化剂在补充标准AD疗法的潜在好处.
主要方法:
- 专家的共识陈述是基于文献综述而制定的.
- 为了评估总结陈述,采用了德尔菲过程.
- 对特定治疗缓和剂的临床数据进行了审查.
主要成果:
- 治疗软化剂含有抗氧化剂等活性成分,提供超出基本保湿的好处.
- 新出现的数据表明,使用furfuryl palmitate缓和治疗可以改善AD症状和患者的生活质量.
- 这些软化剂在各种AD阶段都有潜力,可以补充TCS和全身治疗.
结论:
- 治疗软化剂对亚托邦性皮炎患者来说是一个有价值的治疗选择.
- 它们可能在患有类固醇恐惧症的流行率高的地区特别有益.
- 治疗软化剂的概念可能会随着具有抗炎或抗微生物特性的药物的开发而扩展.
相关概念视频
01:26Atherosclerosis III: Management
311
Management of atherosclerosis involves an integrated strategy encompassing pharmacological treatment, surgical interventions, lifestyle changes, and nutrition therapy to address the multifactorial nature of the disease.Pharmacological TherapyA cornerstone of atherosclerosis management is the use of pharmacological agents. Statins, such as atorvastatin, are pivotal in inhibiting HMG-CoA reductase, an enzyme that catalyzes an initial step in cholesterol synthesis in the liver. This reduction in...
311
01:25Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs
1.7K
Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
1.7K
01:20Asthma: Pathogenesis and Management
1.2K
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
1.2K
01:30Asthma-IV: Diagnostic and Management
3.1K
The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
3.1K
01:30Asthma-IV: Nursing Management
3.7K
The nursing management of asthma is a comprehensive approach that relies heavily on the expertise and dedication of healthcare professionals. It involves thorough assessment, accurate diagnosis, strategic planning, effective implementation, and diligent evaluation. By meticulously following this step-by-step process, healthcare professionals play a crucial role in providing the best possible care and treatment for patients with asthma, enhancing their overall health and well-being.
First, in...
First, in...
3.7K
01:14Changes in Skin Color: Clinical Perspectives
3.3K
The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
3.3K