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Updated: Jan 12, 2026

Functional Cloning Using a Xenopus Oocyte Expression System

Functional Cloning Using a Xenopus Oocyte Expression System

Published on: January 30, 2016

基:25年来,从Xenopus中整合了分子和生物医学数据

Stanley Chu¹, Andrew J Bell², Vaneet Lotay¹

¹Department of Biological Sciences, University of Calgary, Calgary Alberta T2N1N4, Canada.

|November 3, 2025

概括

Xenbase 增强了 Xenopus 研究的知识库,改善了基因组和表型数据的整合,以推进发育生物学和人类健康洞察力.

科学领域:

* 发育生物学发育生物学
* 分子生物学 * 分子生物学
* 基因组学是一个学科.

背景情况:

* Xenbase是Xenopus研究的综合知识库,集成了各种数据类型.
*它旨在支持Xenopus研究,并将研究结果转化为改善人类健康.
*数据集成依赖于核心数据模型和关系映射的本体学.

研究的目的:

*为了支持Xenopus分子,细胞和发育生物学研究.
* 为生物医学生态系统提供Xenopus数据.
* 加速将Xenopus研究转化为人类健康知识.

主要方法:

* 应用FAIR数据原则的专家策划.
*自动化管道和数据处理程序.
* 整合各种数据类型,包括基因组,解剖学,表型和蛋白质.

主要成果:

* 显著改善了Xenopus laevis和Xenopus tropicalis基因组资源的质量.
* 内容类型,软件和系统的改进.
*通过本体学和核心数据模型加强了数据连接.

结论:

*Xenbase为探索DNA变异的医学影响提供了宝贵的资源.
*知识库支持对人类健康受损的根本原因的研究.
*持续的改进确保Xenbase仍然是生物医学界的重要资源.

关键词:

这是Xenopus.公平的数据是公平的.动物模型动物模型我们的数据库数据库数据库数据库.基因组学就是基因组学.知识基础知识库

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Genome-wide Snapshot of Chromatin Regulators and States in Xenopus Embryos by ChIP-Seq

Genome-wide Snapshot of Chromatin Regulators and States in Xenopus Embryos by ChIP-Seq

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Optimized Analysis of Proteins from Xenopus Oocytes and Embryos by Immunoblotting

Optimized Analysis of Proteins from Xenopus Oocytes and Embryos by Immunoblotting

Published on: September 19, 2025

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