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一个用于Trypanosoma cruzi MASP序列注释的算法

Aldana A Cepeda Dean1,2, Virginia Balouz3,4, Carlos Andrés Buscaglia3,4

  • 1Instituto de Investigaciones Biotecnológicas (IIBIO), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentina. acepedadean@iib.unsam.edu.ar.

Methods in molecular biology (Clifton, N.J.)
|November 3, 2025
PubMed
概括

一个新的生物信息学协议准确地识别了T. cruzi.中的粘素相关表面蛋白 (MASP). 这种方法直接作用于寄生虫基因组,简化了蛋白质分析.

关键词:
这个HMM就是HMM.隐藏的马尔科夫模型在MASP MASP上与真相关的表面蛋白质.

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Chagas disease, or American trypanosomiasis, is a vector-borne parasitic infection caused by Trypanosoma cruzi, a flagellated protozoan (kinetoplastid) of the family Trypanosomatidae. The disease is endemic in Latin America, although cases are increasingly reported worldwide due to human migration. Transmission most commonly occurs when feces of infected triatomine bugs contaminate bite wounds or mucosal surfaces; additional routes include congenital, transfusional, transplant-related, and oral...